Instrumentation Available to the Biochemistry Program

 

Chemistry Department Instruments

SPECTROMETRY

  • Bruker Avance 500MHz NMR
  • Thermo Electron Almega Raman Microscope
  • 2 Agilent 8453 UV/Vis Spectrometers
  • Jobin/Yvon Fluoromax-3 Spectrofluorometer
  • Shimadzu UV-2401PC UV-Vis
  • Perkin Elmer 3100 Atomic Absorption, Graphite Furnace
  • Mattson Galaxy 6020 FTIR
  • MIDAC M2501 FTIR Interferometer
  • Perkin Elmer Spectrum One FTIR Spectrometers (2), one with universal ATR attachment
  • Hewlett Packard 8452A Diode Array UV-Vis
  • SPEX 1403 Raman Monochromator
  • Spectrophysics Nd:YAG Laser
  • Nikon Microphot-FX fluorescence/phase contrast/ differential interference contrast microscope equipped with a Spot II digital camera

 

X-RAY DIFFRACTION

  • Rigaku Miniflex X-ray Powder Diffractometer

 

SEPARATIONS

  • Shimadzu LC-10AS High-Performance Liquid Chromatograph
  • Shimadzu QP5050 Gas Chromatograph/Mass Spectrometer
  • Hewlett Packard 5890A/5970B Gas Chromatograph/Mass Spectrometer
  • Hewlett-Packard G1602A Capillary Electrophoresis
  • B/R Teflon Spinning Band Distillation Column
  • ISCO UA-5 UV monitor/Foxy Fraction collector
  • Assorted Fraction Collectors
  • SpeedVac system
  • Assorted Student gas chromatographs

 

BIOCHEMISTRY

  • 2 SoLow –80° Freezers
  • Sorvall RC-5B Centrifuge
  • Walk-in Coldroom
  • Nanopure Water Purifier
  • Jasco P-1020 Polarimeter
  • Coy Anaerobic Glover Box

 

COMPUTATIONAL

  • Workstations
  • SGI Octane/O2 Workstations--5
  • Linux Workstations--12
  • Departmental Computer Lab--20 Apple Macintosh computers, 2 Dell PC’s
  • SGI Altix
  • 32 CPU SGI Altix 350, 32Gb Ram, 1.375 TB of scratch space
  • 16 CPU SGI Altix 350, 32Gb Ram, 1TB of scratch space
  • 16 CPU SGI Altix 350. 16Gb Ram, 0.5TB of scratch space 
  • 2 CPU SGI Altix 350, 8Gb Ram, 230GB of scratch space
  • Total Altix: 66 CPU's, 88GB Ram, 3.105TB of scratch space
  • SGI Origin (irix64)
  • 32 CPU Origin 2000, 16GB Ram, 80Gb of scratch space
  • 64 CPU Origin 2400, 16GB Ram, 89Gb of scratch space
  • 4 CPU Origin 200, 1.5Gb Ram, 36Gb of scratch space
  • 4 CPU Origin 200, 1.5Gb Ram, 36Gb of scratch space
  • 4 CPU Origin 200, 1.5Gb Ram, 36Gb of scratch space
  • 4 CPU Origin 200, 1.5Gb Ram, 36Gb of scratch space
  • 4 CPU Origin 200, 1.5Gb Ram, 36Gb of scratch space
  • Total Irix64: 116 CPU's, 39.5Gb Ram, 350Gb of scratch space

 

MERCURY RESOURCES

  • 32 CPU SGI Origin 300, 32GB Ram, 788Gb of scratch space
  • 4 CPU SGI Origin 300, 2Gb Ram, 63Gb scratch space
  • 28 CPU (generic vendor) Beowulf cluster. Each node has 1 cpu, 512mb Ram, 120 Gb of scratch (shared across all nodes).
  • 156 (38 compute nodes (152), 1 head node (4)) CPU Beowulf cluster from Western Scientific.

Each node has 2 - Dual Core Opteron CPU's (total 4 cpus), 2Gb Ram, and share 2TB of scratch space across all 38 nodes.

Total: 220 CPU's 128Gb Ram, ~4 TB Scratch Space

*Total Cluster Resources: 402 CPU's, 255.5Gb Ram, 7.455TB of scratch space

(* excludes workstation machines)


CALORIMETRY/ELECTROCHEMISTRY

  • Microcal VP Isothermal Calorimeter
  • Perkin Elmer EEG/PAR Potentiostat
  • Parr Bomb Calorimeter

 

SYNTHESIS

  • Innovative Technologies Drybox
  • Five complete vacuum lines
  • Parr Hydrogenation Apparatus
  • Büchi Kugelrohr
  • Rotary Evaporators (13)  

 

Biology Department Instruments

GENOMICS

  • DNA/RNA purification equipment
  • DNA/RNA quantification equipment (GE Nanovue) 
  • PCR (Applied Biosystems 2400, 9700, Veriti & BioRad MyCycler) 
  • Quantitative real-time PCR (Applied Biosystems 7300) 
  • Molecular cloning equipment
  • Agarose gel and southern/northern/western blot detection (BioRad ChemiDoc XRS system)  
  • DNA sequencing (LiCor 4300) 
  • Luminometer with Dual Injectors (2020n) from Turner BioSystems 

 

PROTEOMICS

  •  HPLC with electrochemical, RAM and UV/Vis detection (Shimadzu)
  • Capillary Electrophoresis (HP) 
  • Microplate spectrophotometers (Bio Rad 680XR & BioTec EL311) 
  • Gel electrophoresis equipment (Hoefer PS250, Invitrogen XCell) 
  • Vibrating microtome (Vibratome) 
  • Cryostat 
  • Fluorescent up-right and inverted microscopes (Olympus IX70, Nikon E600) 
  • Tissue culture facility