2018-2019 Seminar Schedule
*All seminars will take place from 3:00-4:00 pm unless otherwise noted*
Sept. 20th, Kap-Sun Yeung, Bristol-Meyers-Squibb: Discovery of BMS-929075 an HCV NS5B Replicase Allosteric Inhibitor Advanced to Phase 1 Clinical Studies
Oct. 4th, Jamie McCabe Dunn '01: Enabling medicinal chemistry as a process chemist
Nov. 1st, Phillip Milner '10, Cornell University: Metal-Organic Frameworks for applications from carbon capture to organic synthesis
Mar. 6th, Robin Kinnel, Hamilton College: ADVENTURES, JOYS AND LESSONS FROM FIFTY YEARS OF RESEARCH
April 24th, Erik Sorenson, Princeton University: TBD
Damian Young, Baylor College of Medicine: "Synthetic Chemistry to Enable Chemical Biology"
P. Andrew Evans, Queen's University: "New Vistas in the Asymmetric Construction of C-C Bonds: Total Synthesis of Complex Bioactive Agents"
Brian Musselman, CEO IonSense Inc.: "Mass Spectrometry the Easy Way"
John Doench '00, Broad Institute: "CRISPR: A New Hope in Functional Genomics"
Matthew Liptak, University of Vermont: "Non- Canonical Heme Oxygenases: A New Chapter of Heme-Oxygen Chemistry"
Jyllian Kemsley, C&E News: "From the Safety Beat: The UCLA Fatality and Beyond"
Leslie Aldrich, The University of Illinois at Chicago: "Development of performance diverse, natural product-like libraries for novel probe discovery"
Harry Gray, California Institute of Technology (James S. Plant Distinguished Scientist Lecture): "Fuel from Sunlight and Water"
Xavier Roy, Columbia University: "Molecular Clusters: Building Blocks for Nanoelectronics and Material Design"
Chuck Jakobsche, Clark University: "From Organic Synthesis to Chemical Biology"l
Marco Allodi '08, University of Chicago: "Using Ultrafast Spectroscopy and Imaging to Uncover Molecular Vibrational Anharmonicity and Excited State Dynamics"
Neil Tomson, University of Pennsylvania: “Incorporating Recent Advances in Coordination Chemistry into Models of Biological and Industrial Dinitrogen Reduction”
Ellen Matson, University of Rochester: “Polyoxometalate-alkoxide clusters as Redox Active Reservoirs”
Andrew Huisman, Union College: “Using single levitated particles to investigate atmospheric aerosols: the physical properties of neat supercooled dicarboxylic acids ”
Rick Geier, Colgate University: “Syntheses of Porphyrinoids with Altered Core Structures”
Steffen Lindert, The Ohio State University: “The Power of Computation in Biochemistry: Elucidation of Atomic Resolution Protein Structures from Sparse Experimental Data"
Casey Londergan, Haverford College: "The outsides and insides of wiggly proteins revealed by vibrational spectroscopy"
Robert Tanguay, Oregon State University: "Using Multidimensional Zebrafish Data to Advance Environmental Health"
Alison Narayan, University of Michigan: "Biocatalysis at the University of Michigan"
Raymond Schaak, The Pennsylvania State University: "Turning Cartoons into Reality: Synthetic Design Tools for Complex Inorganic Nanostructures"
Laura Macmanus-Spencer, Union College: "The photochemical fate of sunscreen chemicals in the aquatic environment"
Onica Legendre, Hunter College: "Olive oil: the answer to curing cancer? Oleocanthal selectively induces LMP in human cancers."
Kendra Avery, City of Hope: "Engineering Antibodies and Antibody Binding Proteins and Peptides for Therapeutic Applications"
Rigoberto Hernandez, Georgia Tech: "Advancing Science Through Diversity" & "Emergent Structure of Nanoparticles"
Leanne (Pasquini) Gilbertson '07, University of Pittsburgh: "Sustainability by Design: Maximizing the Functional Performance & Minimizing the Potential for Adverse Consequences of Emerging Materials"
Ji Ming Wang, National Cancer Institute: "The essential role of G-protein coupled chemoattractant receptors in the progression of cancer and inflammation"
Evan Trivedi, Oakland University: "Fluorescent Pyrrolic Macrocycles for Tumor Imaging: Balancing Optics with Amphiphilicity"
Ruth Nussinov, National Cancer Institute: "Ras signaling: a challenge to the biological sciences"
Shrikanta Chattopadhyay, Broad Institute / Massachusetts General Hospital: "Niche in a Dish: Using Microenvironment-Based Phenotypic Screening to Discover New Cancer Therapeutics"
Bill Miller, University of Richmond: "DNA Polymerase: Nature's Match Maker"
Scott Perrin, National Institutes of Health: "Curvature Induction by the Surface-Bound Antimicrobial Peptides Piscidin 1 and Piscidin 3"
John T. Groves, Princeton University: "How Nature Uses Oxygen - Lessons from Metalloenzymes and Bio-Inspired Catalysts"
Chunyu Wang, Rensselaer Polytechnic Institute: "Structural Mechanism in Alzheimer’s Disease and Protein Autoprocessing"
M. Kevin Brown, Indiana University: "New Methods and Strategies for the Synthesis of Cyclobutanes"
Ken Dill, Stony Brook University:
"A Physical Chemist's Look at how Cells Grow and Evolve" & "The Deep Innovation Engine of Science in America" (Morris Fellow Lecture: Link 1 & Link 2)
George Barnes, Siena College: "Molecular Dynamics Studies of Proton Transfer and Complex Formation during SID"
Ryan Murelli, Brooklyn College: "New Synthetic Methods and Strategies for Drug Discovery and Development"
Dacheng Ren, Syracuse Biomaterials Institute: “Combating bacterial drug resistance by targeting biofilms and persister cells”
Mingji Dai, Purdue University: "New Strategies and Tactics for Efficient and Divergent Synthesis of Bioactive Polycyclic Natural Products"
Mark Dumont, University of Rochester: “G protein couple receptors: How extracellular signals trigger intracellular response”
Dick Zare, Stanford:
"Advances in Ambient Ionization Mass Spectrometry" & "Can we teach creativity?" (Plant Lecture)
Praveen Sethupathy, University of North Carolina: "Small RNAs in Liver Disease"
Mitch Malachowski, University of San Diego: "Metal Complexes: Bioinorganic Models and Metal Organic Frameworks."
Mark Braiman, Syracuse University: "Chemical and biochemical mechanisms for solar energy storage."
Dorothy Beckett, University of Maryland: "Allosteric coupling via long distance communication of disorder-to-order transitions".
Steven Weinreb, Pennsylvania State University: "Synthetic Methodology Involving Amides and Imines"
James Hougland, Syracuse University